Comparisons and class hubs
Receptor classes, structural families and nomenclature, compared on chemistry and published evidence.
- DAC and no DAC: albumin conjugation in the GRF(1-29) analogues
The drug affinity complex is a maleimidopropionyl group on a thirtieth lysine that binds covalently to serum albumin. What that chemistry changed in the published human studies, and what the non-DAC peptide is.
CJC-1295 · reviewed 2026-09-22
- GHRH analogues and ghrelin receptor agonists: two receptors
Sermorelin, tesamorelin and CJC-1295 act at the GHRH receptor; ipamorelin acts at GHSR-1a. Two receptors, two structural families, why the Prohibited List enumerates them separately, and how the evidence differs.
Sermorelin · reviewed 2026-09-22
- Incretin receptor agonist classes: single, dual and triple
Semaglutide, tirzepatide and retatrutide as structural and pharmacological classes: which receptors each engages, the acylation chemistry the three share, and how far the published trial record extends for each.
Semaglutide · reviewed 2026-09-22
- Thymosin β4, the 17–23 fragment and Ac-SDKP: three molecules
Full-length thymosin β4, the N-acetylated 17–23 heptapeptide registered as TB-500, and the N-terminal tetrapeptide Ac-SDKP are three separate substances with three sets of identifiers and three literatures.
TB-500 · reviewed 2026-09-22