United Kingdom

7 compound entries are recorded for this jurisdiction. A compound absent from this page has no verified entry here, which means the position has not been established from a primary source — not that no position exists.

  • Semaglutide

    Approved medicine · MHRA

    Authorised under four brands covering both routes, including an oral tablet for weight management authorised on 11 June 2026 which has no EU equivalent. The indication wording differs from the corresponding EU text for every brand.

    • Wegovy injection and Wegovy tablets are under additional monitoring
    • Wegovy tablets carry no adolescent indication, unlike the UK injectable presentation

    MHRA products database, semaglutide summaries of product characteristics · verified 2026-07-30

  • Tirzepatide

    Approved medicine · MHRA

    Authorised under a single brand across pen, vial and multi-dose pen presentations. The indication is constructed differently from the EU text, using a numbered format and reordering the weight-management clause, so the two are not interchangeable as quoted wording.

    • Under additional monitoring

    MHRA products database, tirzepatide summaries of product characteristics · verified 2026-07-30

  • Orforglipron

    Investigational — no marketing authorisation · MHRA

    No marketing authorisation. The MHRA products database returns no result for either the international nonproprietary name or the United States brand name, and no application has been confirmed from a primary source.

    MHRA products database search result for orforglipron · verified 2026-07-30

  • Retatrutide

    Investigational — no marketing authorisation · MHRA

    No marketing authorisation. The MHRA products database returns no result for retatrutide.

    MHRA products database search result for retatrutide · verified 2026-07-30

  • GHK-Cu

    Cosmetic ingredient · Office for Product Safety and Standards

    Lawful as a cosmetic ingredient in Great Britain. The ingredient appears in none of the annexes to assimilated Regulation (EC) No 1223/2009, which is enforced under the Cosmetic Products Enforcement Regulations 2013. The word tripeptide does not occur anywhere in the Great Britain annexes.

    • Absence from the annexes is not an approval. Compliance rests on the Article 3 general safety obligation, an Article 10 safety report prepared by a qualified assessor, a responsible person established in the territory, notification to the competent authority, and Article 19 labelling using the common ingredient nomenclature
    • Copper is not prohibited as a class. Annex II lists individually named copper substances only, several restricted to hair dye products, and non-nano metallic copper is a permitted Annex IV colorant, reference 132, colour index 77400, without conditions
    • Great Britain has NOT adopted the European Union prohibition on nano and colloidal copper, and Annex II reference numbers have diverged between the two jurisdictions, so entries must not be cross-cited by number
    • Northern Ireland follows the live European Union Regulation rather than the Great Britain consolidation, including the nano copper prohibition, and requires a responsible person established in Northern Ireland or the European Union

    Regulation (EC) No 1223/2009, as assimilated law applying in Great Britain · verified 2026-07-31

  • AHK-Cu

    Cosmetic ingredient · Office for Product Safety and Standards

    Lawful as a cosmetic ingredient in Great Britain on the same basis as any unlisted functional ingredient. It appears in none of the annexes to assimilated Regulation (EC) No 1223/2009, and the word tripeptide does not occur anywhere in the Great Britain annexes.

    • Absence from the annexes is not an approval. Compliance rests on the Article 3 general safety obligation, an Article 10 safety report prepared by a qualified assessor, a responsible person established in the territory, notification to the competent authority, and Article 19 labelling using the common ingredient nomenclature
    • Copper is not prohibited as a class. Annex II lists individually named copper substances only, several restricted to hair dye products, and non-nano metallic copper is a permitted Annex IV colorant, reference 132, colour index 77400, without conditions
    • Great Britain has NOT adopted the European Union prohibition on nano and colloidal copper, and Annex II reference numbers have diverged between the two jurisdictions, so entries must not be cross-cited by number
    • Northern Ireland follows the live European Union Regulation rather than the Great Britain consolidation, including the nano copper prohibition, and requires a responsible person established in Northern Ireland or the European Union
    • The Cosmetic Ingredient Review conclusion reached for Copper Tripeptide-1 does not extend to this compound, and no Great Britain or European Union safety opinion covers it

    Regulation (EC) No 1223/2009, as assimilated law applying in Great Britain · verified 2026-07-31

  • NAD+

    No established classification · Food Standards Agency

    No published position on nicotinamide adenine dinucleotide. Searches of the Food Standards Agency register of novel food authorisations and of the regulated product applications register return no result for it. Great Britain operates a novel food regime separate from the European Union one, and has not followed the 2022 European extension of use for the authorised precursor.

    • Nicotinamide riboside chloride is authorised in Great Britain for food supplements only, a narrower scope than the current European Union entry
    • NMN is not authorised in Great Britain; an application is under risk assessment

    FSA Register of Novel Food Authorisations, entry NOVEL-96 nicotinamide riboside chloride · verified 2026-07-30